In response to a question on MSN Clones I’ve been using Pidgin for multiprotocal IM on Windows and Adium on Apple Mac’s.
My kids still like aMSN and I like how easy it works for people who just want to connect to MSN buddies. However I have way too many people on Google-Talk to use a single protocol client.
Interestingly I’m using Skype for a lot of IM at the moment. After two or three IM’s it’s quicker to initiate a call. I like that functionality.